Exploration of some patients clinical variables.

Overview

Answer_ALS_clinical_data

Exploration of some patients clinical variables.

All the clinical / metadata data is available here: https://data.answerals.org/home

For precision on dataset : AnswerALS.pdf

2 notebooks : Exploration: EDA and build a simple TABLE of patients and mutations. Table_extended : build the TABLE with all the variables (shown in the presentation).

In the folder, all .csv files and cytoscape graph.

Searching possible clusters / patterns / special patients.

To do so, we are using a few variables, and representing patients-variable bipartite graph. Then by using a standard weighted projection on the patients & the variables nodes, we plot the graph of relation between patients & variables.

The chosen variables :

image

Through the lens of a PCA

image image

Bipartite graph

image

Variable weighted projected graph

image

Patients weighted projected graph

image

2 cluster are visible

image

Center of the "big" cluster

image

Full Presentation :

AnswerALS.pdf

You might also like...
PULSE: Self-Supervised Photo Upsampling via Latent Space Exploration of Generative Models
PULSE: Self-Supervised Photo Upsampling via Latent Space Exploration of Generative Models

PULSE: Self-Supervised Photo Upsampling via Latent Space Exploration of Generative Models Code accompanying CVPR'20 paper of the same title. Paper lin

An exploration of log domain "alternative floating point" for hardware ML/AI accelerators.

This repository contains the SystemVerilog RTL, C++, HLS (Intel FPGA OpenCL to wrap RTL code) and Python needed to reproduce the numerical results in

RE3: State Entropy Maximization with Random Encoders for Efficient Exploration

State Entropy Maximization with Random Encoders for Efficient Exploration (RE3) (ICML 2021) Code for State Entropy Maximization with Random Encoders f

Generative Exploration and Exploitation - This is an improved version of GENE.
Generative Exploration and Exploitation - This is an improved version of GENE.

GENE This is an improved version of GENE. In the original version, the states are generated from the decoder of VAE. We have to check whether the gere

Systemic Evolutionary Chemical Space Exploration for Drug Discovery
Systemic Evolutionary Chemical Space Exploration for Drug Discovery

SECSE SECSE: Systemic Evolutionary Chemical Space Explorer Chemical space exploration is a major task of the hit-finding process during the pursuit of

A repository with exploration into using transformers to predict DNA ↔ transcription factor binding

Transcription Factor binding predictions with Attention and Transformers A repository with exploration into using transformers to predict DNA ↔ transc

Learning from Guided Play: A Scheduled Hierarchical Approach for Improving Exploration in Adversarial Imitation Learning Source Code
Learning from Guided Play: A Scheduled Hierarchical Approach for Improving Exploration in Adversarial Imitation Learning Source Code

Learning from Guided Play: A Scheduled Hierarchical Approach for Improving Exploration in Adversarial Imitation Learning Source Code

Multi-robot collaborative exploration and mapping through Voronoi partition and DRL in unknown environment
Multi-robot collaborative exploration and mapping through Voronoi partition and DRL in unknown environment

Voronoi Multi_Robot Collaborate Exploration Introduction In the unknown environment, the cooperative exploration of multiple robots is completed by Vo

Checkout some cool self-projects you can try your hands on to curb your boredom this December!

SoC-Winter Checkout some cool self-projects you can try your hands on to curb your boredom this December! These are short projects that you can do you

Owner
null
Chinese clinical named entity recognition using pre-trained BERT model

Chinese clinical named entity recognition (CNER) using pre-trained BERT model Introduction Code for paper Chinese clinical named entity recognition wi

Xiangyang Li 109 Dec 14, 2022
UmlsBERT: Clinical Domain Knowledge Augmentation of Contextual Embeddings Using the Unified Medical Language System Metathesaurus

UmlsBERT: Clinical Domain Knowledge Augmentation of Contextual Embeddings Using the Unified Medical Language System Metathesaurus General info This is

null 71 Oct 25, 2022
A project for developing transformer-based models for clinical relation extraction

Clinical Relation Extration with Transformers Aim This package is developed for researchers easily to use state-of-the-art transformers models for ext

uf-hobi-informatics-lab 101 Dec 19, 2022
Get a Grip! - A robotic system for remote clinical environments.

Get a Grip! Within clinical environments, sterilization is an essential procedure for disinfecting surgical and medical instruments. For our engineeri

Jay Sharma 1 Jan 5, 2022
NBEATSx: Neural basis expansion analysis with exogenous variables

NBEATSx: Neural basis expansion analysis with exogenous variables We extend the NBEATS model to incorporate exogenous factors. The resulting method, c

Cristian Challu 100 Dec 31, 2022
[ICLR 2021] Rank the Episodes: A Simple Approach for Exploration in Procedurally-Generated Environments.

[ICLR 2021] RAPID: A Simple Approach for Exploration in Reinforcement Learning This is the Tensorflow implementation of ICLR 2021 paper Rank the Episo

Daochen Zha 48 Nov 21, 2022
A mini library for Policy Gradients with Parameter-based Exploration, with reference implementation of the ClipUp optimizer from NNAISENSE.

PGPElib A mini library for Policy Gradients with Parameter-based Exploration [1] and friends. This library serves as a clean re-implementation of the

NNAISENSE 56 Jan 1, 2023
Code for the paper Language as a Cognitive Tool to Imagine Goals in Curiosity Driven Exploration

IMAGINE: Language as a Cognitive Tool to Imagine Goals in Curiosity Driven Exploration This repo contains the code base of the paper Language as a Cog

Flowers Team 26 Dec 22, 2022
Exploration-Exploitation Dilemma Solving Methods

Exploration-Exploitation Dilemma Solving Methods Medium article for this repo - HERE In ths repo I implemented two techniques for tackling mentioned t

Aman Mishra 6 Jan 25, 2022
[Preprint] "Chasing Sparsity in Vision Transformers: An End-to-End Exploration" by Tianlong Chen, Yu Cheng, Zhe Gan, Lu Yuan, Lei Zhang, Zhangyang Wang

Chasing Sparsity in Vision Transformers: An End-to-End Exploration Codes for [Preprint] Chasing Sparsity in Vision Transformers: An End-to-End Explora

VITA 64 Dec 8, 2022